Known IssuesΒΆ
| Issue | Fix Version |
|---|---|
| Paired reads are not getting displayed if Split reads are not present in the data | 6.0.0 |
| The gene track doesn't display properly when the are no genes matching the patient clinical indication | 6.0.0 |
| History of the validation and artefact assessment is not displaying correctly in the Variant List | TBC |
| Cancer Hotspots are not yet available for splice variants or Indels | TBC |
| Tumour morphology and topography is not displayed correctly in the case summary | TBC |
| Option to sort somatic small variants by VAF is missing in the variant list | TBC |
| Tooltip for QC flag column name and values in the germline small variant list is not visible | TBC |
| Clicking on an empty region of the SV chart removes all results from the corresponding variant list | TBC |
| The value for paired or split reads shows as 'Not applicable' for SVs with no SR/PR support | TBC |
| The table of alternative transcript IDs is being sorted page wise rather than table wise | TBC |
Info
Variant filtering for reported variants in tumour first cases in the cDSS may differ from that in HTMLs: in these cases, we apply both somatic and germline prioritisation algorithms to all variants with GEL internal population germline allele frequency under 2%, so all such variants will appear on the cDSS. In the HTMLs and CSV tables, all variants with either GEL internal or gnomAD population germline allele frequency over 1% and no potential effect on cancer predisposition genes (nothing in the "Interpretation as germline" field) are filtered out. We are currently working on fully harmonising the variant lists between cDSS and HTML, and this discrepancy should disappear soon.
Please report any bugs or issues with the DSS via the Genomics England Service Desk.