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Welcome to the cDSS

Here, you can access step-by-step guidance on how to use the Genomics England Cancer Decision Support System (cDSS).

Getting started

  1. Open cancer cases ready for review.
  2. Review case quality, somatic and germline variants detected and global analyses of the case.
  3. Record interpretations of somatic and germline variants identified in the patient.
  4. Download a PDF where variants and/or global analyses plots have been selected for clinical review at GTAB.

Target Audience

Genomic Laboratory Hub (GLH) staff handling the interpretation of Cancer whole genome sequencing (WGS) data using the Genomics England Interpretation Platform.

Other Third Party Audience

The external audience for this document may include medical device regulators and associated agencies in the pursuit of medical device regulatory and standards certification including:

UK Competent Authority: (CAs) the Medicines and Healthcare Products Regulatory Agency (MHRA); Notified Bodies (NBs) such as BSI Group; NHS Digital; the NHS IT regulator in England and Wales. This document may also be requested by existing and prospective Genomics England customers as part of their procurement process. All external distribution of the must be approved by a member of the Quality Improvements and Regulatory Affairs team prior to circulation.

Additional Resources

Interpretation Platform Documentation

Cancer Genome Analysis Guide

Feedback

If you have any feedback on cDSS please raise a ticket via the Genomics England Service Desk.